Abuse potential while combining Carisoprodol with Tramadol

Carisoprodol is the generic version of brand name drug Soma which is primary, skeletal muscle relaxant but is given along with a pain reliever as it boosts up the analgesic’s effect while Tramadol is the generic version of brand name Ultram, a narcotic-like pain reliever. Neither of these medications is a controlled substance, yet may have significant side effects as well as abuse potential.

Tramadol abuse potential

Tramadol works by activating opioid receptors and has been reported to be abused intensely leading to adverse events such as drug dependency and seizures. The tramadol drug has been reported to induce mental cravings, tolerance development and several withdrawal symptoms such as anxiety, insomnia, rigors, diarrhea, upper respiratory tract symptoms, hallucinations, and tremors. The list doesn’t end here. The instant relief providing characteristic along with addictive nature are the key elements that contribute towards tramadol’s abuse potential which is further enhanced by drug interaction with food ingredients as well as other drugs in the body.

Carisoprodol abuse potential

Carisoprodol works through sedation instead of direct relaxation of skeletal muscles. On reaching body, it is further broken down into three major metabolites, out of which one is Meprobamate. This metabolite has a history of abuse potential and is listed under controlled substance. Carisoprodol abuse potential is attributed to Meprobamate’s consumption. When taken alone, Carisoprodol shows no prominent ill-effects on health apart from mild euphoria but on discontinuing consumption abruptly, withdrawal symptoms may occur as it has the property of causing physical dependence. Also, its potential effect on narcotics has been reported to be abused when taken in along with several opioid drugs.

Combined abuse potential of Carisoprodol-Tramadol

Individually, both Carisoprodol, as well as Tramadol, have been found to have some abuse potential in terms of addiction, dependency, and tolerance. But when it comes to combined use of Carisoprodol-Tramadol, the effects may vary as per consumer’s symptoms, severity of pain, physiological condition and the history of substance abuse.

For some, this combination has done wonders by imparting profound relief from intense pains while the other story suggests that the side effects outweigh benefits. These side effects include dizziness, confusion state of mind, drowsiness and problems in concentrating, thinking, making judgments and motor coordination.

It has also been found that concomitant use of these medications can have heightened respiratory-depressant effects or moderate to severe effects on Central Nervous System (CNS). People with a history of drug addiction and/or abuse and elderly are more susceptible to such side effects.

There have been no sufficient scientific data to exactly estimate the drug abuse potential of this combination but more or less, Carisoprodol-Tramadol abuse potential does exist. These effects can be minimized with timely monitoring of mental coordination, alertness, prolonged CNS depressions, as well as respiratory depressions by the healthcare provider. Any changes or abnormalities noticed in daily activities should be consulted with the physician as soon as possible. Also, as the physiology of one person may vary from another and so is the effect of the drug on the body. Therefore, the rule of thumb should be that either it is controlled substance, individual drug or concomitant one, care must be taken that no drug is consumed without recommendation.